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University of Illinois at Urbana-Champaign

Published Journal Articles & Book Chapters

  1. Rich MH, Lee MK, Balance WC, Boppart MD, Kong HJ. Poly(ethylene glycol)-mediated collagen gel mechanics regulates cellular phenotypes in a microchanneled matrix. Biomacromolecules, 18: 2315-23, 2017.
  2. Bower AJ, Mahmassani Z, Zhao Y, Chaney EJ, Marjanovic M, Lee MK, Graf BW, De Lisio M, Kong H, Boppart MD, Boppart SA. In vivo assessment of engineered skin cell delivery with multimodal optical microscopy. Tissue Eng Part C Methods, 23: 434-42, 2017.
  3. Mahmassani ZS, Son K, Pincu Y, Munroe M, Drnevich J, Chen J, Boppart MD. a7b1 Integrin regulation of gene transcription in skeletal muscle following an acute bout of eccentric exercise. Am J Physiol Cell Physiol, 312: C638-50, 2017.
  4. Chung HR, Wu PT, Fitschen PJ, Kistler BM, Park H, Wilund KR, Boppart MD. The impact of exercise training on statin-associated skeletal muscle myopathy. PLoS One, 11: e0168065, 2016.
  5. Munroe M, Pincu Y, Merritt J, Cobert A, Brander R, Jensen T, Rhodes J, and Boppart MD. Impact of &beta-hydroxy &beta-methylbutyrate (HMB) on age-related functional deficits in mice. Exp Gerontol, 87: 57-66, 2016.
  6. Garg K, Boppart MD. Influence of exercise and aging on extracellular matrix composition in the skeletal muscle stem cell niche. J Appl Physiol, 121: 1053-58, 2016. Invited review.
  7. Li J, Pincu Y, Marjanovic M, Bower AJ, Chaney EJ, Jensen T, Boppart MD, Boppart SA. In vivo evaluation of adipose- and muscle-derived stem cells as a treatment for nonhealing diabetic wounds using multimodal microscopy. J Biomed Opt, 21: 86006, 2016.
  8. Pincu Y, Huntsman HD, Zou K, De Lisio M, Mahmassani ZS, Munroe MR, Garg K, Jensen T, Boppart MD. Diet-induced obesity regulates adipose-resident stromal cell quantity and extracellular matrix gene expression. Stem Cell Res 17: 181-90, 2016.
  9. Boppart MD, De Lisio M, Witkowski S. Exercise and Stem Cells. In: Bouchard C, Ed. Progress in Molecular Biology and Translational Science. Volume 135: Molecular and Cellular Regulation of Adaptation to Exercise. Elsevier Inc., 2015, pp. 423-56.
  10. Farup J, De Lisio M, Rahbek SK, Bjerre J, Vendelbo MH, Boppart MD, Vissing K. Pericyte response to contraction mode-specific resistance exercise training in human skeletal muscle. J Appl Physiol, 119: 1053-63, 2015.
  11. De Lisio M, Farup J, Sukiennik RA, Clevenger N, Nallabelli J, Belson B, Ryan K, Rahbek SK, de Paoli F, Vissing K, Boppart MD. The acute response of pericytes to muscle-damaging eccentric contraction and protein supplementation in human skeletal muscle. J Appl Physiol 119: 900-7, 2015.
  12. Pincu Y, Linden MA, Woods JA, T Baynard, Boppart MD. The effects of high fat diet and moderate exercise on TGFbeta1 and collagen deposition in mouse skeletal muscle. Cytokine 73:23-9, 2015.
  13. Caliari SR, Weisgerber DW, Grier WK, Mahmassani Z, Boppart MD, Harley BAC. Collagen scaffolds incorporating coincident gradations of instructive structural and biochemical cues for osteotendinous junction engineering. Adv Healthc Mater 4: 831-7, 2015.
  14. Ogasawara R, Nakazato K, Sato K, Boppart M, Fujita S. Resistance exercise increases active MMP and β1-integrin protein expression in skeletal muscle. Physiol Rep, 2: e12212, 2014.
  15. Zhao Y, Marjanovic M, Chaney EJ, Graf BW, Mahmassani Z, Boppart MD, Boppart SA. Longitudinal label-free tracking of cell death dynamics in living engineered human skin tissue with a multimodal microscope. Biomed Opt Express, 5: 3699-716, 2014.
  16. Zou K*, De Lisio M*, Huntsman HD, Pincu Y, Mahmassani Z, Miller M, Olatunbosun D, Jensen T, Boppart MD. Laminin-111 improves skeletal muscle stem cell quantity and function following eccentric exercise. Stem Cell Translational Medicine, 3 (9), 1013-1022, 2014. (*equal contribution as first author)
  17. Zou K, Huntsman HD, Valero MC, Adams J, Skelton J, De Lisio M, Jensen T, Boppart MD. Mesenchymal stem cells augment the adaptive response to eccentric exercise. Med Sci Sports Exerc, 47 (2), 315-325, 2014.
  18. Lee MK, Rich MH, Shkumatov A, Liu SC, Jeong JH, LeyTheng L, Boppart MD, Gillette MU, Bashir J, Lee J, Kong H. Glacier moraine formation-mimicking colloidal particle assembly in microchanneled, bioactive hydrogel for vascular and neural patterning. Adv Health Mater, Epub ahead of print, 2014.
  19. De Lisio M, Jensen T, Sukiennik AR, Huntsman HD, Boppart MD. Substrate and strain alter the muscle-derived mesenchymal stem cell secretome to promote myogenesis. Stem Cell Res Ther, 5: 74, 2014.
  20. Graf BW, Chaney EJ, Marjanovic M, Adie SG, De Lisio M, Valero MC, Boppart MD, Boppart SA. Long-term time-lapse multimodal intravital imaging of wound healing and bone-marrow-derived cell dynamics in skin. Technology, 1 (1), 8-19, 2013.
  21. Graf BW, Bower AJ, Chaney EJ, Marjanovic M, Adie SG, De Lisio M, Valero MC, Boppart MD, Boppart SA. In vivo multimodal microscopy for detecting bone-marrow-derived cell contribution to skin regeneration. J Biophotonics, 7(1-2):96-102, 2014.
  22. Boppart MD, De Lisio M, Zou K, Huntsman HD. Defining a role for non-satellite stem cells in the regulation of muscle repair following exercise. Front Physiol, 4:310, 2013. Review.
  23. Graf BW, Chaney EJ, Marjanovic M, De Lisio M, Valero MC, Boppart MD, Boppart SA. In vivo imaging of immune cell dynamics in skin in response to zinc-oxide nanoparticle exposure. Biomed Opt Express, 4(10):1817-28, 2013.
  24. Zhao Y, Bower AJ, Graf BW, Boppart MD, Boppart SA. Imaging and tracking of bone marrow-derived immune and stem cells. In: Turken K, Ed. Methods in Molecular Biology. Humana Press, 2013; pp. 1-20.
  25. Huntsman HD, Zachwieja N, Zou K, Ripchik P, Valero MC, De Lisio M, Boppart MD. Mesenchymal stem cells contribute to vascular growth in skeletal muscle in response to eccentric exercise. Am J Physiol Heart Circ Physiol, 304(1):H72-81, 2013.
  26. Zhao Y, BW Graf, E Chaney, Z Mahmassani, E Antoniadou, R Devolder, H Kong, MD Boppart, and SA Boppart. Integrated multimodal optical microscopy for structural and functional imaging of engineered and natural skin. J Biophotonics, 5: 437-448, 2012.
  27. Valero MC, Huntsman HD, Liu J, Zou K, Boppart MD. Eccentric exercise facilitates mesenchymal stem cell appearance in skeletal muscle. PLoS One, 7(1):e29760, 2012.
  28. Liu J, Milner DJ, Boppart MD, Ross RS, Kaufman SJ. β1D chain increases α7β1 integrin and laminin and protects against sarcolemmal damage in mdx mice. Hum Mol Genet 21: 1592-1603, 2012.
  29. Zou K, B Meador, B Johnson, C Valero, HD Huntsman, K Huey, and MD Boppart. The α7β1 integrin increases muscle fiber hypertrophy following multiple bouts of eccentric exercise. J Appl Physiol 111: 1134-1141, 2011.
  30. Lueders T, K Zou, HD Huntsman, B Meador, Z Mahmassani, M Abel, MC Valero, K Huey, and MD Boppart. The α7β1 integrin accelerates fiber hypertrophy and myogenesis following a single bout of eccentric exercise. Am J Physiol Cell Physiol 301: C938-946, 2011.
  31. Boppart MD, DJ Burkin, and SJ Kaufman. Activation of AKT signaling promotes cell growth and survival in α7β1 integrin-mediated alleviation of muscular dystrophy. Biochimica Biophysica Acta (Molecular Basis of Disease) 1812(4): 439-446, 2011.
  32. Ding H, Z Wang, F Nguyen, SA Boppart, LJ Millet, MU Gillette, J Liu, MD Boppart, and G Popescu. Fourier Transform Light Scattering (FTLS) of Cells and Tissues. J Comp Theo Nanosci, 7:2501-2511, 2010. (Invited)
  33. Ding H, E Bearl, Z Wang, LJ Millet, MU Gillette, J Liu, MD Boppart, and G Popescu. Fourier transform light scattering of biological structures and dynamics. IEEE J Select Topics Quant Electronics, 16: 909-918, 2010. (Invited)
  34. Ge Y, AL Wu, C Warnes, J Liu, C Zhang, H Kawasome, N Terada, MD Boppart, CJ Schoenherr, and J Chen. mTOR regulates skeletal muscle regeneration through kinase-dependent and kinase-independent mechanisms. Am J Physiol Cell Physiol, 297: C1434-1444, 2009.
  35. Boppart MD, SE Volker, N Alexander, DJ Burkin, and SJ Kaufman. Exercise promotes α7 integrin gene transcription and protection in skeletal muscle. Am J Physiol Regul Integr Comp Physiol, 295: R1623-1630, 2008.
  36. Boppart MD, DJ Burkin, and SJ Kaufman. α7β1 Integrin inhibits mechanotransduction and prevents skeletal muscle injury in vivo. Am J Physiol Cell Physiol 290: C1660-1665, 2006.
  37. Pasquesi JJ, S Schlachter, MD Boppart, EJ Chaney, SJ Kaufman, and SA Boppart. In vivo detection of exercise-induced ultrastructural changes in genetically-altered murine skeletal muscle using polarization-sensitive optical coherence tomography. Optics Express, 14: 1547-1556, 2006.
  38. Fujii N, MD Boppart, SD Dufresne, PF Crowley, AC Jozsi, K Sakamoto, H Miyazaki, MF Hirshman, and LJ Goodyear. Overexpression or ablation of JNK in skeletal muscle has no effect on glycogen synthase activity. Am J Physiol Cell Physiol, 287: C200-208, 2004.
  39. Boppart MD, MF Hirshman, RA Fielding, and LJ Goodyear. Static stretch markedly increases c-Jun NH2-terminal kinase (JNK) activity and p38 phosphorylation in rat skeletal muscle. Am J Physiol Cell Physiol 280: C352-C358, 2001.
  40. Boppart MD, S Asp, JFP Wojtaszewski, RA Fielding, T Mohr, and LJ Goodyear. Marathon running transiently increases c-Jun NH2-terminal kinase and p38 kinase activities in human skeletal muscle. J Physiol 526.3: 663-669, 2000.
  41. Boppart MD, D Aronson, J Bean, LJ Goodyear, and RA Fielding. Eccentric exercise markedly increases c-Jun NH2-terminal kinase activity in human skeletal muscle. J Appl Physiol 87: 1668-1673, 1999.
  42. Hayashi T, SD Dufresne, DA Aronson, DJ Sherwood, MF Hirshman, MD Boppart, RA Fielding, and LJ Goodyear. Intracellular Signaling Pathways in Contracting Skeletal Muscle. In: Hargreaves M, Thompson M, Eds. Biochemistry of Exercise X. Champaign, IL: Human Kinetics Publishers, 1999; pp. 19-34.
  43. Boppart MD, DB Kimmel, JA Yee, and DM Cullen. Time course of osteoblast appearance after in vivo mechanical loading. Bone 23(5): 409-15, 1998.
  44. Aronson D, MD Boppart, SD Dufresne, RA Fielding, and LJ Goodyear. Exercise stimulates c-Jun NH2 kinase activity and c-Jun transcriptional activity in human skeletal muscle. Biochem Biophys Res Comm 251: 106-110, 1998.
  45. Napoli R, L Gibson, MF Hirshman, MD Boppart, SD Dufresne, ES Horton, and LJ Goodyear. Epinephrine and insulin stimulate different mitogen-activated protein kinase signaling pathways in rat skeletal muscle. Diabetes 47: 1549-1554, 1998.
  46. Kvidera (Boppart) MD and GB Carey. Glutamine synthetase in rat epididymal tissue. Proceedings of the Society for Experimental Biology and Medicine, 206(4): 360-364, 1994.

Grant Funding

1997-1998       Dudley Allen Sargent Alumni Association Research Fund, "Upstream regulators of the c-Jun kinase signaling pathway in skeletal muscle", PI Marni Boppart.

1998-1999       American College of Sports Medicine Graduate Student Foundation Grant, "Molecular regulators of JNK signaling in skeletal muscle", PI Marni Boppart.

2006-2009       Illinois Regenerative Medicine Institute, "Therapeutic implementation of mesoangioblast stem cells in muscular dystrophy", co-PI’s Marni Boppart and Suzanne Berry.

2008                Beckman Foundation, “Bio-Rad ChemiDoc XRS System for high resolution multicolor fluorescent imaging”, PI Marni Boppart.

2009-2010       Mary Neer Jane Fund, “Utilization of a novel multipotent stem cell as therapy in the alleviation of muscular dystrophy”, PI Marni Boppart.    

2009-2010       Arnold O. Beckman Award (UIUC Campus Research Board), “Utilization of a novel multipotent stem cell as therapy in the alleviation of sarcopenia”, PI Marni Boppart.

2009-2011       National Science Foundation, “3-D optical tracking of bone marrow derived skin stem cells”, PI Stephen Boppart, co-PI Marni Boppart.

2009-2013       Ellison Medical Foundation, “Utilization of a7 integrin-derived stem cells as therapy for the alleviation of sarcopenia, PI Marni Boppart, co-PIs Stephen Boppart and Bradford Schwartz.

2009                National Science Foundation (Major Instrumentation Grant), “Acquisition of a molecular imaging instrument for dynamic material and biological systems (PET), PI Stephen Boppart (4 co-PIs + 49 users).

2009                National Institutes of Health (S10 – Shared Instrumentation Grant), “High-resolution in vivo ultrasound imaging using VisualSonics VEVO2100 system, PI William O’Brien (9 major + 5 minor users; M Boppart major user).

2010                National Science Foundation (IGERT), “Cellular & Molecular Mechanics and Bio-Nanotechnology (CMMB)”, Integrative Graduate Education and Research Traineeship (IGERT) to support graduate students in the study of cellular mechanotransduction in collaboration with the University of Illinois Center for Cellular Biomechanics (23 UIUC professors).

2010-2013       National Science Foundation, “Advanced optical imaging of 3-D cell dynamics in engineered skin”, PI Stephen Boppart, co-PIs Marni Boppart, Hyun Joon Kong, and Mark Shannon.

2011-2013       National Science Foundation IGERT-CMMB Graduate Student Fellowship (to Heather Huntsman), “Alleviation of sarcopenia using mechanical strain-induced myogenic stem cells”, PI Marni Boppart, co-PIs Hyun Joon Kong, Stephen Boppart, Matthew Wheeler, Derek Milner.

2011                Center on Health, Aging, and Disability (CHAD), “The impact of hypercholesterolemia and physical activity on statin-associated skeletal muscle myopathy”, PI Marni Boppart, co-PIs Wilund K and Sivaguru M. 

2012-2015       Center for Nutrition, Learning and Memory/Abbott Laboratories, "Nutritional Enhancement of Cognition through Stem Cells", PI Marni Boppart, co-PI Justin Rhodes.

2012-2013       American College of Sports Medicine Foundation Grant, "Use of laminin-111 to increase skeletal muscle hypertrophy", PI Kai Zou, Faculty Mentor Marni Boppart.

2013-2015       National Institutes of Health R21, “Patterning instructive biomolecular cues into collagen scaffolds for tendon insertion regeneration”, PI Brendan Harley, co-PI Marni Boppart.

2013-2014       Diabetic Complications Consortium Pilot and Feasibility Program, “Molecular imaging of stem cell induced reversal of vascular complications in DM”, PI Wawrzyniec Dobrucki, co-PIs Marni Boppart and Andrew Smith.

2014-2015       American College of Sports Medicine Foundation Grant, “Adipose resident pericyte response to high fat diet and exercise”, PI Yair Pincu, Faculty Mentor Marni Boppart.

2014-2016       National Institutes of Health R21, “Alpha7 integrin-mediated hypertrophic signaling and growth in skeletal muscle”, PI Marni Boppart.

2014-2015       Carver Biotechnology Center Fluidigm C1 Single Cell Genomics Grant Promotion, “Characterization of two types of pericytes in adipose tissue using multicolor flow cytometry and single cell gene expression approaches”, PI Yair Pincu, Faculty Mentor Marni Boppart.

2014                UIUC OVCR Equipment Grant, “In vivo 3-D optical and x-ray CT imaging system”, PI Stephen Boppart, multiple users listed.

2014                UIUC OVCR Equipment Grant, “All-in-one plate reader/imager for high throughput screening”, PI Zeynep Madak-Ergogan, multiple users listed.

2015                Mayo Clinic Summer Undergraduate Research Fellowship (SURF), PI Kelly Twohig, Faculty Mentor Marni Boppart.

2015-2020       National Institutes of Health K23, “Translational study of vocal exercise dose response”, PI Aaron Johnson, Faulty Mentors Marni Boppart and Eddie McAuley.

2015-2017       National Institutes of Health R21, “Development of a liposomal nanostimulator to improve stem cell-based revascularization therapies”, co-I’s Hyunjoon Kong and Marni Boppart.

2016-2018       Arnold O. Beckman Award (UIUC Campus Research Board), “Development of a stem cell-based therapy to improve recovery following immobilization”, PI Marni Boppart.

  University of Illinois Urbana-Champaign | Beckman Institute  | Department of Kinesiology and Community Health